| UGroup Ubadge | Bedfordview | Name badges, keyrings, engraving | |
| Uhambo Training Solutions | Sasolburg | Training Service Provider | |
| Ujala Consulting | Johannesburg | Full service marketing / advertising consultancy | |
| Ukuanda Holdings | Cape Town | Recruitment | |
| Ukushilela All Print Solutions | Cape Town | Print Consultant, Print Management & Distribution | |
| Ukuyila Design | | We deliver high quality Graphic and Web Design | |
| Ukwenza Designs | Cape Town | Branding Specialists, office and home | |
| Ulivo & Co Communications | Johannesburg | Public Relations and Communications | |
| Ullerstam Trading | Kempton Park | Design of sheet metal parts and products | |
| Ulovane Environmental Training | Sidbury | Field, Trails, Marine and Bird Guide Training | |
| Ultimate AV Solutions | Vanderbijlpark | Digital Signage and AV Solutions | |
| Ultitech | Johannesburg | Online tech store | |
| Ultra Boost Juice Reviews | | Ultra Boost Juice reviews | |
| Ultra Control Valves | Edenvale | Automatic Water Control Valves and other valves | |
| Ultra Design | Pretoria | Marketing | |
| Ultra Mobile plan. | Cranbury | Ultra Mobile plan | |
| Ultra Mobile plan.. | Cranbury | Ultra Mobile plan | |
| Ultra Vision Brand Activators | Johannesburg | Below-The-Line Marketing | |
| ULTRAEVENT TECHNICAL SOLUTIONS | Cape Town | Suppliers of tech equipment to the event industry | |
| Ultrarecovery | | investment recovery service | |
| Ulwandle HR Consultants | | HR Consulting | |
| Umad | | Digital Media Advertising & Design | |
| Umbhaco | Cape Town | Designing, manufacturing traditional Xhosa attire | |
| Umbono Conference and Events | Kwamhlanga | Conferencing & Event Management | |
| Umdoko Internet | Sandton City | Specialised development on modern software | |
| Umfa | Johannesburg | UMFA is a National Utility Management Company | |
| Umjikelo Recruitment Services | Pretoria | Recruitment agency, Executive search, headhunting | |
| Umlambo Media | DURBABN | Dynamic advertising professional service | |
| Umlingo Productions | Johannesburg | Video Production | |
| Umvini Academy | Newcastle | Matric Upgrade & Re-write Programme | |
| Unahina Solutions | | Purchase Order Funding | |
| Unboxed Construction & Signs | Johannesburg | Construction & Signage | |
| Unboxed Distribution | Sandton | Distribution | |
| Unboxed Pets | Sandton | Pets | |
| Unboxed Publishing Consultancy | Pretoria | Publishing | |
| Unbranded Africa | KwaZulu-Natal | Event Management, Sponsorship & Marketing | |
| Uncle Ross Tutors | | Tutoring Service | |
| Undaku | | Web Development | |
| Under Pressure Soft Wash and Power Washing | Radnor | Pressure washing | |
| Underground Music Association | | 163 West Street Pietermarizburg | |
| Underground Press | Durban | Publishing | |
| Unfold Durban | Durban | Digital Marketing | |
| Uniclox | Alberton | Time and Attendance, access Control | |
| Uniclox (Pty.) | Alberton | Time and Attendance, Access Control | |
| Unik Furniture Rentals | Durban | Furniture Rentals | |
| UNION | Cape Town | Brand communication | |
| Union Electrical Wholesalers | Germiston | Supply Full Range of Electrical Items | |
| Uniq Outdoor | Johannesburg | Media owner with out-of-home (outdoor) space. | |
| Uniqaya Lifestyle | | e-commerce | |
| Unique Avcom | Germiston | Audio Visual & Event Management | |
| Unique Cosmetics | Cape Town | hair treatment for damaged hair | |
| Unique MMO | Cape Town | Industrial gas, diving gas, gas storage equipment | |
| Unique Performance Projects | Cape Town | home improvement | |
| Unique Pest Control Services | Cape Town | Pest control services around Capetown | |
| Unistal | | unistal | |
| Unitec Africa | Roodepoort | it company south africa, it services in south afri | |
| United Glassblowers | Vaal Marina | Manufacturers of scientific glassware | |
| United Spectrum | | Laser Hardening Machine in chennai | |
| United Transport Services | Johannesburg | United Transport Services | |
| Unitrade 313 | Durban | Manufacture and sale of meat and meat products | |
| Universal Kitchen and Granite | | Retailer | |
| Universal Link Group | Cape Town | Courier /Mailhouse /Import & Export | |
| Universal Motor Cars LV | | Automotive | |
| University Bahamas | | Marketing | |
| Uniwebserve | Cape Town | Web Hosting, Domain Registration | |
| Uniwebserve Web Hosting South Afirca | Cape Town | Web hosting, domain registration, South Africa | |
| UNKNOWN Design Agency | Johannesburg | Branding, Art Direction, Web Design, Print Design | |
| Unlimited Badges and Signs | Pretoria | Button Badges and Vehicle branding | |
| Unlimited force marketing | Claremont | Sales | |
| UNO SEWING | Johannesburg | Sewing machines and spare parts | |
| Unplugg IT Solutions | Northriding | Software Development, IT Solutions | |
| Untamed Creative Society | Centurion | Bespoke Marketing Agency | |
| Untamed Events Management | Cape Town | We provide a range of services for every occasion. | |
| UOM Marketing | Durban | Creative, route to market and project management | |
| Up Grade Md Health | | Up Grade Md Health | |
| Up Stream Marketing | Centurion | Marketing | |
| Update Marketing | Alberton, South Africa | Leaflets delivery | |
| Update Website | Alberton | Website design | |
| Update Website | Alberton | Website design | |
| Update Website | Alberton | Website design | |
| Updeedco | | Updeedco | |
| Upington Ateljee | Upington | Multi Media Graphic Design & Corporate Identity | |
| Upright Hand | | Rental of scaffolding and machinery | |
| UPrint SA | Durban | promotional gift suppliers and digital printing | |
| Upstage Productions | Johannesburg | Event Technical Equipment Hire | |
| Upstart Entrepreneur | | Mentorship, Coaching, Online Training, Resources | |
| Uptech | Edenvale | Uninterruptible Power Technology | |
| Uptown Marketing | Johannesburg | Graphic and Web Design Services | |
| Upvanta Electrician | Baldwin Park | Electrician | |
| UR Image Photography | Roodepoort | UR IMAGE PHOTOGRAPHY | |
| Urban Cinematography - Durban | Durban | Videography | |
